Koch`s Postulates and his Contribution to Microbiology
Koch`sPostulates and his Contribution to Microbiology
Koch`spostulates and his contribution to microbiology
Koch contributed greatly to microbiology especially through Koch’spostulates where he proved the “germ theory of disease”postulated by Pasteur by cultivating anthrax bacteria (Boundlessn.d.). The theory suggests that microorganisms cause infectiousdiseases. Koch found out that cattle infected with anthrax had highquantities of bacillus anthraces in their blood thus, he noticedthat he could spread anthrax from an infected animal to a healthyanimal by shooting up a healthy animal from the infected one as wellas grow the bacteria in a nutrient broth. Based on these tests, herecognized a two-way connection between a microorganism and adisease. In this regards, Boundless (n.d.) suggests that Koch’spostulates establish that a microbe or other microorganisms must beexistent in all situations of a disease i.e. microbes must be inplenty in all creatures suffering from a disease but absent inhealthy animals. Secondly, one can sequester a pathogen from thesickly host and then grow the pathogen in pure culture.
Then,Breitschwerdt et al. (2013) contend that Koch postulated that amicrobe from the pure culture should cause the illness when injectedinto a healthy, vulnerable laboratory animal and finally Koch foundout that one must re-isolate pathogens from the new host and shownthem to be alike as the initially injected microbe. However, a bodyof proof that fulfills these postulates is satisfactory but notessential to establish a relationship as Koch proved in cases ofcholera and tuberculosis (Breitschwerdt et al., 2013 Segre, 2013).In this regards, Koch contributed considerably to the field ofmicrobiology especially in studies involving tuberculosis and thespread of anthrax. In fact, he helped to increase people’scomprehension of blood-borne diseases as well as suggested numerousways of suppression and treatment. In addition, Segre (2013) assertsthat Koch’s findings of the causes of anthrax and tuberculosishelped greatly in the treatment of these diseases. Today, hispostulates remain the foundation of microbiology hence, his greatcontribution to microbiology.
Boundless. (n.d.). Boundless Microbiology. Retrieved February 3,2015, fromhttps://www.boundless.com/microbiology/textbooks/boundless-microbiology-textbook/
Breitschwerdt, E. B., Linder, K. L., Day, M. J., Maggi, R. G.,Chomel, B. B., & Kempf, V. A. J. (2013). Koch`s postulates andthe pathogenesis of comparative infectious disease causationassociated with Bartonella species. Journal of comparativepathology, 148(2), 115-125.
Segre, J. A. (2013). What Does It Take to Satisfy Koch’s PostulatesTwo Centuries Later & quest Microbial Genomics andPropionibacteria acnes. Journal of InvestigativeDermatology, 133(9), 2141-2142.